N-CHLOROACETYL 5-METHOXYTRYPTAMINE (ISAMIDE) - SELECTIVE ANTAGONIST OF 5-HYDROXYTRYPTAMINE IN THE RAT UTERUS
Isamide, the N-chloracetyl derivative of 5-methoxytryptamine, produced a dose-dependent competitive blockade of uterine contractions in vitro induced by 5-HT [hydroxytryptamine]. The pA2 value for the 5-HT-isamide interaction was 4.42. The blockade was short-lasting and reversible; after recovery, a...
| Autores principales: | , , |
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| Formato: | Artículo (Article) |
| Idioma: | Inglés (English) |
| Publicado: |
2025
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| Materias: | |
| Acceso en línea: | https://repositorio.uc.cl/handle/11534/100093 |