Inherent Immune Cell Variation Within Colonic Segments Presents Challenges for Clinical Trial Design

Background and Aims: Intestinal biopsy sampling during IBD trials represents a valuable adjunct strategy for understanding drug responses at the tissue level. Given the length and distinctive embryonic origins of the proximal and distal colon, we investigated whether inherent regional differences of...

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Detalles Bibliográficos
Autores principales: Tyler, Christopher J., Guzman, Mauricio, Lundborg, Luke R., Yeasmin, Shaila, Perez-Jeldres, Tamara, Yarur, Andres, Behm, Brian, Dulai, Parambir S., Patel, Derek, Bamias, Giorgos, Rivera-Nieves, Jesus
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2025
Materias:
mass cytometry
lamina propria
randomised controlled trials
03 Good Health and Well-being
03 Salud y bienestar
Acceso en línea:https://repositorio.uc.cl/handle/11534/100348

Internet

https://repositorio.uc.cl/handle/11534/100348

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