Extracellular vesicles derived from fat-laden hepatocytes undergoing chemical hypoxia promote a pro-fibrotic phenotype in hepatic stellate cells

Background: The transition from steatosis to non-alcoholic steatohepatitis (NASH) is a key issue in non-alcoholic fatty liver disease (NAFLD). Observations in patients with obstructive sleep apnea syndrome (OSAS) suggest that hypoxia contributes to progression to NASH and liver fibrosis, and the rel...

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Detalles Bibliográficos
Autores principales: Hernandez, Alejandra, Reyes, Daniela, Geng, Yana, Pablo Arab, Juan, Cabrera, Daniel, Sepulveda, Rolando, Solis, Nancy, Buist-Homan, Manon, Arrese, Marco, Moshage, Han
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2025
Materias:
Nonalcoholic fatty liver disease
Liver fibrosis
Hypoxia
Extracellular vesicles
03 Good Health and Well-being
03 Salud y bienestar
Acceso en línea:https://repositorio.uc.cl/handle/11534/100483

Internet

https://repositorio.uc.cl/handle/11534/100483

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