Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation

Regenerative responses predispose tissues to tumor formation by largely unknown mechanisms. High-mobility group box 1 (HMGB1) is a danger-associated molecular pattern contributing to inflammatory pathologies. We show that HMGB1 derived from keratinocytes, but not myeloid cells, delays cutaneous woun...

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Detalles Bibliográficos
Autores principales: Hoste, Esther, Maueroder, Christian, van Hove, Lisette, Catrysse, Leen, Vikkula, Hanna-Kaisa, Sze, Mozes, Maes, Bastiaan, Karjosukarso, Dyah, Martens, Liesbet, Goncalves, Amanda, Parthoens, Eef, Roelandt, Ria, Declercq, Wim, Fuentes, Ignacia, Palisson, Francis, Gonzalez, Sergio, Salas-Alanis, Julio C., Boon, Louis, Huebener, Peter, Mulder, Klaas Willem, Ravichandran, Kodi, Saeys, Yvan, Schwabe, Robert Felix, van Loo, Geert
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2025
Materias:
03 Good Health and Well-being
03 Salud y bienestar
Acceso en línea:https://repositorio.uc.cl/handle/11534/100820

Internet

https://repositorio.uc.cl/handle/11534/100820

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