c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling

During the development of the sympathetic nervous system, signals from tropomyosin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate survival and connectivity. During this process, nerve growth factor (NGF)-TrkA signaling in axons communicates NGF-mediated trop...

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Detalles Bibliográficos
Autores principales: Escudero, C. A., Cabeza, C., Moya-Alvarado, G., Maloney, M. T., Flores, C. M., Wu, C., Court, F. A., Mobley, W. C., Bronfman, F. C.
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2025
Materias:
Acceso en línea:https://repositorio.uc.cl/handle/11534/101131