ANTIPROLIFERATIVE ACTIVITY OF NEW 6-BROMINE DERIVATIVES OF 7-ANILINO-1-ARYLISOQUINOLINEQUINONES

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A variety of 6-bromine-containing 7-anilino-1-arylisoquinolinequinones 2a-g were synthesized to evaluate their half-wave potentials and in vitro antiproliferative activity on gastric and leukemia cancer cell lines. The new compounds displayed significant IC50 values in the range: 1.31 to 11.04 mu M....

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Detalles Bibliográficos
Autores principales: Andrea Ibacache, Juana, Valderrama, Jaime A., Arancibia, Veronica, Theoduloz, Cristina, Muccioli, Giulio G., Benites, Julio
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2025
Materias:
Isoquinolinequinones
half-wave potentials
MTT assay
antiproliferative activity
03 Good Health and Well-being
03 Salud y bienestar
Acceso en línea:https://repositorio.uc.cl/handle/11534/101383

Internet

https://repositorio.uc.cl/handle/11534/101383

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