Tetrahydrohyperforin Increases Adult Hippocampal Neurogenesis in Wild-Type and APPswe/PS1 ΔE9 Mice

Tetrahydrohyperforin (IDN5706), a semi-synthetic derivative of hyperforin, has shown neuroprotective properties preventing the impairment of synaptic plasticity and cognitive decline in an in vivo model of Alzheimer's disease (AD). Considering the reported role of adult neurogenesis in the plas...

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Detalles Bibliográficos
Autores principales: Abbott, Ana C., Toledo, Carla Calderon, Aranguiz, Florencia C., Inestrosa, Nibaldo C., Varela-Nallar, Lorena
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2025
Materias:
Alzheimer's disease
hippocampus
long-term memory
neural progenitor cells
neurogenesis
tetrahydrohyperforin
03 Good Health and Well-being
03 Salud y bienestar
Acceso en línea:https://repositorio.uc.cl/handle/11534/101797

Internet

https://repositorio.uc.cl/handle/11534/101797

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