Coordinated Endothelial Nitric Oxide Synthase Activation by Translocation and Phosphorylation Determines Flow-Induced Nitric Oxide Production in Resistance Vessels

Background/Aims: Endothelial nitric oxide synthase (eNOS) is associated with caveolin-1 (Cav-1) in plasma membrane. We tested the hypothesis that eNOS activation by shear stress in resistance vessels depends on synchronized phosphorylation, dissociation from Cav-1 and translocation of the membrane-b...

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Detalles Bibliográficos
Autores principales: Figueroa, Xavier F., Gonzalez, Daniel R., Puebla, Mariela, Acevedo, Juan P., Rojas-Libano, Daniel, Duran, Walter N., Boric, Mauricio P.
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2025
Materias:
Endothelial cells
Resistance vessels
Ca2+
Shear stress
Endothelial nitric oxide synthase subcellular location
03 Good Health and Well-being
03 Salud y bienestar
Acceso en línea:https://repositorio.uc.cl/handle/11534/101916

Internet

https://repositorio.uc.cl/handle/11534/101916

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