New Pyridone-Based Derivatives as Cannabinoid Receptor Type 2 Agonists

The activation of the human cannabinoid receptor type II (CB2R) is known to mediate analgesic and anti-inflammatory processes without the central adverse effects related to cannabinoid receptor type I (CB1R). In this work we describe the synthesis and evaluation of a novel series of N-aryl-2-pyridon...

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Detalles Bibliográficos
Autores principales: Faundez Parraguez, Manuel, Alarcon Miranda, Carlos, Cho, Young Hwa, Pessoa Mahana, Hernan, Gallardo Garrido, Carlos, Chung, Hery, Faundez, Mario, Pessoa Mahana, David
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: MDPI 2024
Materias:
cannabinoids
2-pyridone
synthesis
CB2R agonists
ENDOCANNABINOID SYSTEM
SELECTIVE LIGANDS
CB2 RECEPTOR
IDENTIFICATION
HETEROCYCLES
DESIGN
POTENT
DRUGS
03 Good Health and Well-being
03 Salud y bienestar
Acceso en línea:https://repositorio.uc.cl/handle/11534/80023

Internet

https://repositorio.uc.cl/handle/11534/80023

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