Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands
A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 compounds displayed high affinitie
Autores principales: | , , , , , , , |
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Formato: | Artículo (Article) |
Idioma: | Inglés (English) |
Publicado: |
2024
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Materias: | |
Acceso en línea: | https://repositorio.uc.cl/handle/11534/86421 |