Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands

A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 compounds displayed high affinitie

Detalles Bibliográficos
Autores principales: Espinosa Bustos, Christian, Iturriaga Vásquez, Patricio, Lagos, Carlos, Mella Raipán, Jaime, Pessoa Mahana, Carlos David, Pessoa Mahana, Hernán, Recabarren Gajardo, Gonzalo Iván, Romero Parra, Javier Hernán
Formato: Artículo (Article)
Idioma:Inglés (English)
Publicado: 2024
Materias:
Acceso en línea:https://repositorio.uc.cl/handle/11534/86421